You’ll notice watermarks on a lot of stock imagery or professional photography. You probably come across watermarks a lot more than you realize. In other cases, a digital watermark may act as a stamp, to indicate the status of a document, with terms like “VOID,” “COPY,” or “SAMPLE.” This ensures that important documents are never mishandled, helping you keep your work organized as you take it from draft to finalization. Much like a painter will mark their work with a signature, digital watermarking is a way to get your name out and heighten brand awareness, so you know that any time your work is shared, say on Instagram for example, your name or brand is always attached to it. On the other end, watermarking can simply be used as a branding tactic. This means that people can still preview your work before purchasing it, without the risk of them stealing it. On one end, watermarking helps protect the copyright of your work and ensures that it cannot be reused or altered without your permission. There are a couple of key reasons why you might need to watermark a document or image. Traditionally, a watermark was only visible when the paper was held up to the light or when it was wet, and the process of watermarking paper occurred while the paper was wet-hence the term we still use today. While the watermarking process is mostly digital these days, the term “watermarking” itself dates back centuries. Let’s take a look at a few reasons why watermarking images and documents is important, and explore how to create a watermark that’s effective for your work. Watermarking is the process of superimposing a logo or piece of text atop a document or image file, and it’s an important process when it comes to both the copyright protection and marketing of digital works.
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By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application (ANDA). Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant.Ī Reference Listed Drug (RLD) is an approved drug product to which new generic versions are compared to show that they are bioequivalent. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation.Įxclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. Ask your health care provider for advice if you are unsure about the online purchase of any medication.Ī drug patent is assigned by the U.S. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. These medications may be counterfeit and potentially unsafe. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Drisdol. The following products are equivalent to Drisdol: ergocalciferol capsule oral Has a generic version of Drisdol been approved? Drisdol is a brand name of ergocalciferol, approved by the FDA in the following formulation(s): DRISDOL (ergocalciferol - capsule oral) With all these big changes happening across the world to Universal, hopefully, soon that will be carried over to the United States as well. Hyde.Throughout the subsequent 101 years, Univeral horror movies have continued to shape the horror landscape and revolutionize what audiences love about horror over and over again. Who knows? Maybe by the time this park opens, we'll actually have the Avatar sequel we've been waiting for. Universal Studios has been on the cutting edge of horror for well over a century dating all the way back to 1912s short film Dr. However, because nothing is confirmed yet, take everything with a grain of salt. There haven’t been any updates on Universal’s end as to when construction might continue or when an official opening date is set, but if there are other rides and theme areas opening in other parts of the world, it might not be that much of a hunch to think construction could start back up again. There doesn’t seem to be any new construction on the ground, and everything seems to be a dirt path as of late. Recently, Twitter posts from Bioreconstruct have shown aerial shots of the construction site for the new park, and it looks pretty abandoned. The launch date was pushed back to 2024, but things aren’t looking too good for the new park in general. But now because of the COVID-19 pandemic, construction has halted on the new park. It was originally slated to open in 2023 with plenty of new rides and lands featuring all of our favorite movies, with construction continuing throughout the years. The new park, under the name of Universal’s Epic Universe, was to be bigger than the other theme parks and located right down the road from both Universal Studios and Islands of Adventure. Universal Studios Resort in Orlando announced way back in 2019 that they were going to be building a whole new theme park, one that was supposed allegedly to be their “most immersive and innovative yet” compared to their other parks there. 1 of 8 Be the First to Know Sign up now for exclusive giveaways, advance screenings, sneak-peeks and much, much more. (Image credit: The mock-up for Universal's Epic Universe.) Universal’s Epic Universe Might Continue Construction In Orlando The word comes from Renaissance Latin gnomus, which first appears in A Book on Nymphs, Sylphs, Pygmies, and Salamanders, and on the Other Spirits by Paracelsus, published posthumously in Nysa in 1566 (and again in the Johannes Huser edition of 1589–1591 from an autograph by Paracelsus). ĭiminutive statues of gnomes introduced as lawn ornaments during the 19th century grew in popularity during the 20th century and came to be known as garden gnomes. Typically small humanoids who live underground, their characteristics are reinterpreted to suit various storytellers and artists. Gnom mit Zeitung und Tabakspfeife (English: Gnome with newspaper and tobacco pipe) by Heinrich Schlitt (1923)Ī gnome / n oʊ m/ is a mythological creature and diminutive spirit in Renaissance magic and alchemy, first introduced by Paracelsus in the 16th century and later adopted by authors including those of modern fantasy literature. You can buy it now on your 3DS for, well, six golden coins. It’s not without its irregularities – holding “up” to jump higher? In a Mario game?! – but Super Mario Land 2: Six Golden Coins is a charming, expansive and replayable handheld experience, with typically superb graphics and sound. The castle stage leading up to him is surprisingly intense, too, especially given how easy-breezy Land 2 is otherwise. Indeed, Wario is the final boss of the game, and in an interesting twist he uses Mario’s own power-ups against him in a multi-phase battle. Perhaps the game’s most notable legacy is the introduction of perennial franchise favourite, Wario, here in a unambiguously antagonistic role. The Honey-I-Shrunk-The-Plumber brilliance of the Macro Zone, the yōkai-filled Pumpkin Zone that pits Mario against sentient Jason Voorhees masks, the sheer freewheeling escapism of the hidden Space Zone culminating in a rematch with Tatanga (from Super Mario Land)… it’s all glorious stuff. There’s a rich vein of imagination running through it, with every “Zone” on the map distinct and memorable. A brilliant, beguiling bit of Weird Nintendo, filled with secrets and interesting detours. However, as mentioned, Link’s Awakening got me to boot it up again for another look and it turns out I was right the first time. 3, or even its immediate predecessor Super Mario Land. I found it terribly easy and lacking in the tight play control of Super Mario Bros. I used to love this game as a child, but in my older teenage years I dismissed it for being “un-Mario”, for its unusual feel by comparison to the console games. In a not-very-roundabout way, this led me back to Super Mario Land 2: 6 Golden Coins. MariotoYoshinoBoukenLand.mp4: 1 09:17: 256.0M iathumb.jpg: 1 09:20: 14.2K: super-mario-world-mario-yoshis-adventure-land-1991archive.torrent: 0 05:57: 22.3K: super-mario-world-mario-yoshis-adventure-land-1991files.xml: 0 05:57: 13. Bill & Ted's Excellent Gameboy Adventure. The recent (excellent) remake of The Legend of Zelda: Link’s Awakening got me ter thinkin’ about the other Game Boy classics I used to enjoy. Atlantis Word Processor allows you to use the undo, redo and search functions, as well as change the viewing mode and manage toolbars.īut you can also insert page numbers, symbols, hyperlinks, table of contents, footnotes, date and time, along with fields, as well as switch to full screen mode.Īdditionally, you can change character case and the language, make file associations, install Atlantis Word Processor on a removable drive, reconfigure program shortcuts and customize toolbars, as well as use tools like spellcheck, autocorrect and hyphenation.ĭocuments can be saved with the RTF, DOC, DOCX, COD and TXT formats. The interface of the program is familiar and easy to navigate through. Intuitive, safe and reliable, superfast, portable and entirely customizable, Atlantis will be the perfect companion for your word processing tasks. Turn any document into an eBook with just a few mouse clicks! Make eBooks for a living, or just create eBooks to read on your iPad or another eBook reader. Compose rich-formatted documents from scratch, or edit existing MS Word documents, and send them to colleagues, customers, partners, friends. In addition to PET/CT scan, narrow-band imaging endoscopy should be considered in head and neck patients at high risk for developing second primary esophageal cancer. PET/CT scan was inferior to narrow-band imaging endoscopy in detecting second primary esophageal cancer in head and neck cancer patients. Hypopharyngeal or laryngeal location of the primary head and neck cancer was the only risk factor for developing second primary esophageal cancer. The respective sensitivity, specificity, and area under the curve for detecting suspicious esophageal lesions were 33.33, 97.73%, and 0.655 for PET/CT scan, and 100.0, 84.85%, and 0.924 for narrow-band imaging endoscopy. The final pathologic diagnoses were esophageal squamous cell carcinoma in 10 and high-grade dysplasia in 5. ResultsĪ total of 147 subjects were included in the analysis suspicious esophageal lesions were identified by PET/CT scan in 8 (5.44%) and by narrow-band imaging in 35 (23.81%). Descriptive statistics, receiver operating characteristic curve analysis, logistic regression analysis, independent Student’s t-test, and Kaplan–Meier survival analysis were conducted with MedCalc Statistical Software. Methodsįrom November 2015 to November 2018, all head and neck cancer patients who underwent both PET/CT scan and narrow-band imaging endoscopy at Changhua Christian Hospital were retrospectively enrolled. We aimed to compare PET/CT scan and narrow-band imaging endoscopy for the detection of esophageal cancer in head and neck cancer patients. Narrow-band imaging endoscopy is an accurate and convenient technique for esophageal examination. Although Positron emission tomography (PET)/computed tomography (CT) scan is commonly conducted in head and neck patients, its ability to detect early esophageal cancer is limited. Second primary cancer of the esophagus is frequent in head and neck patients, especially in high-risk populations, and has a great impact on the prognosis. Read/write disk image: Allows you to add files to the disk image after it’s created. Sparse disk image: Creates an expandable file that shrinks and grows as needed. Sparse bundle disk image: Same as a sparse disk image (below), but the directory data for the image is stored differently. To encrypt the disk image, click the Encryption pop-up menu, then choose an encryption option.Ĭlick the Partitions pop-up menu, then choose a partition layout.Ĭlick the Image Format pop-up menu, then choose an option: If the disk image will be used with a Mac or Windows computer and is 32 GB or less, choose MS-DOS (FAT) if it’s over 32 GB, choose ExFAT. 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Upgrade your Samsung Galaxy phone with fast and easy content transfer Just Download, Click and Go: Smart Switch is up and running in seconds, allowing you to transfer content easily and with no cost or fees. Smart Switch gives you the peace of mind that your apps have been transferred.įree Content Transfer Service, Easy Download Within this large universe of apps, Smart Switch helps you find your favorite apps so that you do not have to search for them individually. For example, there are more than 700,000 apps available on Google Play. Most people are unaware of the universe of apps available on Samsung smartphones. You can transfer personal content and apps from the comfort of your own home and at your own time. With Smart Switch's easy-to-use, intuitive content transfer tool, you have the freedom to switch from other smartphone platforms without fear of losing your personal content. With Smart Switch, you can transfer your personal data, media and apps with one service, without having to use multiple tools. Smart Switch offers a simple, do-it-yourself migration tool that you can install at home. Other content transfer tools are time consuming. Plus, Smart Switch helps you find your favorite apps or suggest similar ones on Google Play. You can also read about all the essential privacy features and our guide to whether you should upgrade to an iPhone 13. The early version of the OS brings a redesigned Notification Summary, updates for emergency calling and a few privacy-related changes with App Privacy Reports, according to GSMArena.įor more about iOS 15 and the new iPhones, check out our iOS 15 review. The latest beta is for Apple's iOS 15.2, and it's available now for testers and developers. Then you should be able to find the latest beta version by going to Settings > General > Software update and selecting Download and Install. 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